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Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells
Clinical translation would require trials in cardiac patient populations with appropriate safety monitoring given theoretical concerns about blood pressure effects and vascular remodeling
While both freezing and high heat are not recommended, short-term exposure to ambient temperature extremes during shipping is unlikely to degrade the integrity of this product due to its stable composition
Rajagopal, R.E., Balasubramanian, M., Kalyanaraman, S.: Raw turmeric and pure curcumin: a comparison of embryonic cytotoxicity in zebrafish
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