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While there might occasionally be minor statistical differences in the *average magnitude* of weight lost between sexes in some specific analyses (factors like baseline body composition can play a role), the overall conclusion is that the medication is robustly effective across both groups compared to placebo
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As expected based on its ability to sharply reduce the body weight and normalize the glucose levels, semaglutide lowered the risk of heart attacks, strokes and cardiovascular deaths by as much as 20%
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