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Most protocols dose by injection close to the site of injury (subcutaneous), though no human pharmacokinetic standard exists
Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity
That said, these therapies offer an important tool for shared decision-makingespecially for those struggling with injectable adherence or lifestyle modifications
HbA 1c change was 2.2, 1.8 and 0.9 percentage points respectively
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