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Ozempic is approved for adults with type 2 diabetes rather than specifically for weight loss

The oral bioavailability is roughly 1%, which is why the oral doses (3 mg, 7 mg, 14 mg daily) appear higher than the injectable doses but deliver similar systemic exposure

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However, despite these results, Novo Nordisks shares declined post-announcement, as investors had anticipated even stronger outcomes, particularly in the T2D cohort, where the efficacy lagged behind emerging triple agonists like retatrutide