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Improves Blood Sugar Control This prevents sugar spikes and excessive hunger

Acknowledgements We thank MGH Executive Committee on Research (ECOR) Interim Support Funding to X.W

Cell culture Primary human umbilical vein endothelial cells (HUVECs) (National Stem Cell Translational Resource Center, Shanghai, China, #DFSC-EC-01), Primary human Coronary Artery Endothelial Cells (HCAECs) (American Type Culture Collection, Manassas, VA, #PCS-100-020), and murine lung microvascular endothelial cells (MLMECs) were cultured in Endothelial Cell Medium (ECM) (Sciencell, Faraday Ave, Carlsbad, #1001)

The data often reveals patterns that appetite suppression alone cannot overcome