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This scoping review aimed to identify and describe clinical evidence on renal outcomes associated with GLP-1-based therapies in adults with type 2 diabetes and/or overweight/obesity, with or without CKD
Activation of colonic GLP-1 receptors slows peristalsis (the muscle contractions that move stool), increases water absorption, and can decrease rectal sensitivity to the urge to defecate
This is not to alarm you but to ensure that chronic acid exposure has not caused changes to the esophageal lining that need specific monitoring or treatment
Intensify your hydration and oral care strategies around dose increases
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