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The effect is dose-dependent and reversible (after discontinuation, pigmentation subsides over weeks to months)
Standard turnaround is 24-48 hours for most providers
The only FDA-approved oral GLP-1 is semaglutide (Rybelsus) for diabetes
Proposed mechanisms include improvements in endothelial function, reduction in systemic inflammation, favourable effects on blood pressure and lipid profiles, and direct actions on cardiac and vascular tissues expressing GLP-1 receptors
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