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3 Thyroidbrain axis pathophysiology and neurological manifestations The major mechanistic routes linking thyroid dysfunction to neuropsychiatric manifestations are summarized in Figure 2, highlighting disrupted hormone transport/activation in the brain, neurotransmitter imbalance, oxidative stressneuroinflammation, and bloodbrain barrier vulnerability
Because Coptis contains berberine, palmatine, coptisine, and jatrorrhizine, it shows powerful activity against bacteria, fungi, and protozoa
doi: 10.1007/s10067-019-04681-4 67 CookADLouisCRobinsonMJSalehRSleemanMAHamiltonJA
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