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Despite the success of glucagon-like peptide-1 receptor agonists (GLP-1RAs), many patients fail to achieve or sustain sufficient weight reduction with current therapies

This ubiquitous pathological process of oxidative stress is particularly significant in the progression of neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD)

This article summarizes topical peptides with proven efficacy in controlled in vivo studies

Anti-inflammatory pathway overlap each compound has reported anti-inflammatory effects through different pathways in preclinical models