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For statistical comparisons, two-tailed Students t-tests were employed for two-group comparisons, while one-way or two-way ANOVA with Bonferroni correction was used for comparisons involving three or more groups

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Analysis of these samples by the Cambridge team showed that around 40% of these patients had raised levels of INSL5, even though they had had bile acid malabsorption ruled out, and these patients responded best to ondansetron