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Smaller, more frequent meals are usually easier than three large ones
& Tjandra, N
Metformin reduces hepatic glucose production and improves insulin sensitivity in muscle tissue, while GLP-1 drugs slow gastric emptying and enhance pancreatic insulin secretion
This trial confirmed that women randomised to the metformin group achieved superior glycaemic control (mean HbA1c 41mmol/mol versus 43.2mmol/mol in the placebo group at 34 weeks of gestation) and required less insulin (1.1 units/kg versus 1.5units/kg in the placebo group
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