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Wegovy (semaglutide 2.4 mg) is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, as an adjunct to a reduced-calorie diet and increased physical activity

Therefore, in this study GLP-1R expression in human organs was assessed through measurement of accumulation of 68 Ga-NODAGA-exendin-4 ( 68 Ga-exendin) by positron emission tomography/computed tomography (PET/CT)

These symptoms can affect up to 30-45% of patients during dose escalation (varying by medication and dose) and can lead to significant fluid losses if not managed appropriately

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