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Finally, obese rats and individuals operated on Roux-en-Y gastric bypass and SG display a new gastric mucosa phenotype with hyperplasia of the mucus neck cells concomitant with increased density of GLP-1 positive cells
Messier SP, et al
When the body perceives sustained energy scarcity, it adapts by conserving fuel, increasing appetite, and becoming more efficient at storing fat when intake rises
The shift in practice toward more holistic care and treatment of cardiometabolic risk factors, instead of treating diabetes or obesity alone, creates significant market potential for dual GLP-1/amylin therapy, which could be used to treat multiple aspects of metabolic syndrome at once and offer cardiovascular and renal protective benefits
