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Tirzepatide is not a hormone replacement therapy but influences metabolic hormones indirectly through its dual GIP/GLP-1 receptor actions, improving insulin secretion, reducing glucagon, and affecting appetite-regulating pathways
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Two people can weigh the same but have vastly different hormonal profiles, cardiovascular fitness levels, and sexual function depending on how much of their weight is fat versus muscle
(If your Wegovy denial is for weight loss rather than MASH, see our Wegovy coverage guide for weight management instead.) There are real bright spots, though
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