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Icariin, as the primary bioactive component of Epimedium brevicornu Maxim., has been shown to stimulate melanogenic activity and behave as a strong TYR activator[264]
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Liraglutide also reduced endothelial tight junction protein barriers, ameliorated ox-LDL induced endothelial monolayer permeability, and inhibited ox-LDL induced expression of vascular adhesion molecules (E-selectin and vascular cell adhesion molecule- 1), preventing ox-LDL induced monocyte adhesion to endothelial cells [57]
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