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Several observational studies have associated higher intakes of fish with benefits related to cognitive performance (165, 166) and cognitive decline (167, 168), as well as with lower risks of some types of dementia, including Alzheimers disease (166, 169-171)
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The STEP trial program examining higher-dose semaglutide (2.4 mg weekly) for weight management demonstrated mean weight loss of 12% to 15% over 68 weeks in adults with obesity, significantly exceeding placebo
For instance, investigations into the efficacy of compounds like Rehmannioside A or the role of HMGB1 in astrocyte-mediated iron dysregulation have been conducted in mice subjected to transient MCAO, albeit with varying occlusion times (e.g., 90 min
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