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One possible scenario is the metabolic cofactor NADPH, which is known to be required not only for lipid synthesis but also for the function of antioxidant reductases, such as glutathione reductase (GSR) and thioredoxin reductase (TXNRD) 86
F., Schmidt, W
When copper is in excess, it can cause oxidative stress and damage to cells, which increases the demand for glutathione to neutralize the free radicals produced
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