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GLP-1 receptor agonist medications like semaglutide and tirzepatide mimic this hormone at therapeutic levels, creating a powerful, sustained effect that your body's natural GLP-1 alone can't achieve
The retatrutide phase 2 body-composition substudy showed lean-mass loss in line with the total weight loss, without evidence of the medication causing extra lean mass losses
Some patients experience relative hypoglycaemiablood glucose lower than their previous baselinewhich can trigger hunger signals as the body adapts to improved glucose control
Target blood ketone levels for nutritional ketosis: 0.5 to 3.0 millimoles per liter
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