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Compared with the overnight pre-dose fasting period employed in the reference arm (night30 min), shorter pre-dose fasting periods of 2, 4, and 6 h in the 2 h30 min, 4 h30 min, and 6 h30 min treatment arms resulted in significantly lower semaglutide AUC 024h and C max on Day 10 (estimated treatment ratio ranges: 0.120.43 and 0.120.44, respectively
Bacteriostatic water adds 0.9% benzyl alcohol, a preservative that inhibits bacterial growth and supports repeated-access use from a single vial
This is not a conscious dietary choice
This is a genuine safety issue
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