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Insulin and glucagon are hormones that regulate blood glucose levels
In the case of alcohol the mechanism is well described: ethanol metabolism involving the CYP2E1 enzyme releases free radicals, and these reduce the level of reduced glutathione in the liver (Lieber, Drug Metabolism Reviews 2004, PMID 15554233)
Jewell JL, Kim YC, Russell RC, Yu F, Park HW, Plouffe SW et al
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