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However, while central pharmacodynamics is an important factor influencing drug intake, peripheral pharmacokinetics can also have a profound effect on intake and even neural response to the same drug 56,57
GLP-1-related hair loss usually manifests as telogen effluvium 24 months after starting treatment or significant weight loss
The abnormal signal pathways will lead to excessive production of FFAs and ROS in adipocytes and hepatocytes, which is a milestone of the first step to develop MASH (Portincasa et al., 2024)
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