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Prior studies have experimentally confirmed that Deferasirox can significantly reduce iron content in the brain tissue of APP/PS1 HAMP/ mice, alleviate mitochondrial morphological damage, and improve learning and memory ability (Zou et al., 2019)
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some investigations report reduced ceramide concentrations in plasma (Wojewodka et al., 2011), while others demonstrate accumulation of long-chain ceramide species in pulmonary tissues (Veltman et al., 2021)
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