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The central nervous system effects reduce appetite and food cravings at the brain level, finally giving you control over the urges that have sabotaged previous attempts at weight loss

Most GLP-1 medication protocols involve gradual dose escalation over several weeks or months

If tiredness is still severe after eight weeks at a stable dose, it's worth speaking to your SheMed clinician persistent fatigue at that stage is less likely to be purely medication-related and may have another cause worth investigating