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By replicating GLP-1s natural activity, Ozempic reduces appetite, increases satiety (the feeling of fullness), and helps control food intake
High-sugar, high-fat (HSHF) diets significantly lead to an imbalance in the ratio of bacteria in the phylum Acidobacteria, Firmicutes and Thick-walled bacteria to those in the phylum Anaplasma, Aspergillus, Cyanobacteria, and Actinobacteria, which impairs the gut barrier function, and activates microglial cells in the brain, generating inflammation and affecting the cholinergic system to increase the risk of cognitive dysfunction (58, 59)
Mechanisms Underlying Weight Loss-Induced Bone Loss Numerous human studies have demonstrated that both disease-induced weight loss and common weight control strategies may have significant negative impacts on the skeletal system
Blood was collected into vacutainer tubes containing EDTA by venipuncture, immediately placed on the ice, and centrifuged at 800 rpm for 15 min at room temperature
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