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Until rigorous clinical trial data become available, any use of tirzepatide for BED remains speculative and off-label, requiring careful consideration of the risk-benefit profile in individual patients

The results have been striking: GHK-Cu has been shown to modulate the expression of more than 4,000 human genes, with the net effect being a return toward expression patterns associated with younger, healthier tissue.6 The pathways most consistently affected include antioxidant defense (upregulation of catalase, superoxide dismutase, and glutathione synthesis), DNA damage repair, extracellular matrix remodeling, and anti-inflammatory signaling

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Mol Cell Biochem 388:19 Sandford EC, Muntz A, Craig JP (2021) Therapeutic potential of castor oil in managing blepharitis, meibomian gland dysfunction and dry eye