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PQQ treatment of TAC-operated mice, however, was sufficient to significantly reduce the extent of mitochondrial outer membrane rupture and to increase the number of visible mitochondrial cristae (Figure 2A)
Only about one in 10 participants in the trials that made these drugs famous was 65 or older, which means information about benefits and side effects in the 60-and-older population is limited
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In response, leading pharmas have announced massive capacity expansions: Novo Nordisk plans a $4.1 billion manufacturing facility in North Carolina ( [5] ) (opening ~2029), and Lilly has committed over $15 billion for new plants in Indiana, Wisconsin, Pennsylvania, and Alabama ( [6] ) ( [7] ) ( [8] ) ( [9] )
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