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In its announcement, which came Friday afternoon, the FDA noted that safety and efficacy of Wegovy in the new indication were based on a trial comprising 17,600 patients randomized to receive either Novos drug or placebo, as well as standard medical treatment and lifestyle counseling
GLP-1s increased the risk for thyroid C-cell tumors in studies of lab rats, but whether they cause these cancers in humans is unknown
Clinical research suggests that multi-drug therapies often result in greater weight loss than single-drug therapies because they target different biological pathways
Limitations of any dosing guidance, including this page The reconstitution math is arithmetic, not validation
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