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Long-term potentiation (LTP), which Dihexa enhances, has been shown to stimulate proliferation of progenitor cells in the dentate gyrus and promote survival of newly born neurons, suggesting Dihexa may facilitate neural regeneration through multiple complementary mechanisms
Until Phase II and III results emerge with proper endpoints (mucosal healing rates, histologic remission, patient-reported outcomes), the evidence base will remain preclinical
SC (subcutaneous): less commonly used in foundational rodent studies but present in some protocols
Steiger, A., et al
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