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81 Additionally, vitamin C is a strong antioxidant that can modulate gut inflammation and may be associated with improved bone mineral density
Goodarzi et al
Pimentel-Filho FR, Ramos-Dias JC, Ninno FB, Faanha CF, Liberman B, Lengyel AM
These two substitutions , the Nle4 and D-Phe7 modifications and were introduced through the systematic structure-activity relationship programme in Victor Hrubys laboratory at the University of Arizona that established the pharmacophore requirements for melanocortin receptor agonism and produced MT-1 as a more potent, metabolically stable, and pharmacologically tractable research tool than native -MSH
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