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Additionally, the participants were in the preparatory phase for upcoming competitions, which made them an ideal sample for assessing the effects of supplementation on performance in an elite athletic population

SIRT3 increases the expression of manganese superoxide dismutase (MnSOD) and catalase (CAT) by deacetylating the transcription factor FOXO3a, and finally decreases ROS levels in the myocardium (Sundaresan et al., 2009)

Metabolomics: beyond biomarkers and towards mechanisms