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A randomized trial using the GLP-1 agonist exenatide in people with IIH showed that intracranial pressure dropped within hours to days of dosing, far too quickly to be explained by any weight changes
Secondary efficacy outcomes included change in body weight following initiation of GLP-1 RA therapy
The follicular phase that precedes it, with rising estrogen and low progesterone, is generally similar
Consider this scenario: a patient six months into semaglutide has lost 34 pounds but notices their strength in the gym has declined and they feel their muscle tone has reduced
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