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Alongside Brazil, Canada is one of the first countries in which patents for GLP-1 blockbusters are expiring albeit initially only for the indication of diabetes
Secondary outcomes included cardiovascular mortality, all-cause mortality, non-fatal myocardial infarction, non-fatal stroke, hospitalisation for heart failure, and adverse events
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Conversely, depression is associated with elevated mtDNA deletions, aberrant mtDNA copy number and oxidative mtDNA damage (113, 118, 119)
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