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Bariatric surgery Bariatric surgery encompasses a range of surgical interventions designed to induce significant weight loss in individuals with severe obesity, particularly when conventional approaches such as pharmacotherapy and lifestyle modification have proven ineffective

The distinct mode of CTR and AMYR engagement by Cagri revealed in the current study, together with the correlated distinctions in functional responses at individual receptors, is likely to be important in the differentiated, high efficacy, of Cagri as a first-in-class obesity drug in both preclinical animal models and in treatment of obese patients in clinical trials 2,3,4

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1d, 2, 3, 4, 5d and 10 ) , and DOX+(SP + L-car) ( Figs