Loomba R, Hartman ML, Lawitz EJ, Vuppalanchi R, Boursier J, Bugianesi E et al
There are forms of hydroquinone, manufactured here in the good old USA, that are safe at the 1-2% limit, when coupled with other protective ingredients
Enteroendocrine cells (EECs), the microbiota, and metabolites produced by the microbiota constitute a complex signaling system [13] that involves the enteric plexus, CNS afferents and efferents, and the modulation of numerous brain nuclei like the nucleus tractus solitarius, hypothalamus, thalamus, and many others directly involved in the control of glucose and energy homeostasis [14]
Most patients (93%) tolerate side effects well enough to continue treatment