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[28] Summary of the role of glutathione as a skin-lightening agent While there is no published data for intravenous glutathione, the results of the three randomized controlled trials mentioned above have provided grade Ib and 2b evidence in favour of the skin-lightening effects of topical and oral glutathione, with no significant adverse effects [Table - 1]

The most dramatic results typically appear between months three and six, not during those first few weeks

Studies suggest that AFU may be more accurate because it measures all viable cells, even ones that may not be culturable

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