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L-carnitine prevents metabolic steatohepatitis in obese diabetic KK-A (y) mice
Semaglutide-loaded nanoparticles have been found in experimental models to improve glucose homeostasis and insulin sensitivity, reduce liver inflammation and oxidative stress, and manage diabetic cardiomyopathy and other metabolic disorders
In individuals with obesity, at a daily dose of 50 mg, it achieved a 17.4% reduction in body weight over 68 weeks of treatment in the OASIS 1 trial37 (Table 1), attributed to its appetite-suppressing and satiety-enhancing effects
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