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Molecular subgroups: [16] Group 1: vestibular (has significant higher rate of 22q loss)

Phase 3 TRIUMPH-4 (NCT05931367) reported 28.7% body weight loss at 12 mg, 26.4% at 9 mg, vs 2.1% placebo at 68 weeks

Dry and pruritic skin is a common clinical manifestation of SS, with vasculitis being the second most common cutaneous manifestation, and histological examination usually confirms the diagnosis of leukocytoclastic vasculitis (LCV) [284]

Kalilight: multifunctional anti-pollution & lightening active Kalilight (inci name: hydroxyapatite, glutathione, cysteine ) is a speciality composed of a biomimetic mineral based on hydroxyapatite (mineral physiologically expressed in teeth and bones and widely used in the bio-medical field with various purposes including drug delivery system, bone/dental remineraliser and anti-ageing active via mesotherapy) functionalized with molecules with an anti-oxidant and detoxifying action such as Glutathione and Cysteine