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Clinicians should exercise heightened caution when considering these compounds in patients receiving anticoagulant or antiplatelet therapy, given their possible influence on hemostasis and wound-healing dynamics

Protein-tyrosine nitration is a post-translational chemical modification process for the highly selective non-enzymatic introduction of a nitro group (-NO 2 ) into the side chain by peroxynitrite (ONOO - ), a short-lived biomolecule generated by the rapid reaction of NO with superoxide radicals in vivo 40,41

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