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In PsO, clinical studies evaluating GLP-1RAs such as liraglutide and semaglutide have reported significant improvements in PASI scores and histopathological skin features, effects that appear to be at least partially independent of weight loss ( Given the prominent role of IL-17driven inflammation in obese PsA patients, GLP-1RAs may also enhance the efficacy of biologic agents targeting these pathways

Phase 3 trials are ongoing and will provide more definitive efficacy and safety data

There's prevention I'm a healthy weight, I'm just starting to see those pounds creep on a little bit

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