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In an experimental murine model of schistosomiasis, cytokine production in PBMC supernatants of infected patients showed an elevation of IL-5 production, which was higher than that induced by soluble egg antigens alone (Reis et al., 2008)
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Although continued treatment is necessary for patients to benefit, uncertainty remains regarding rates of treatment discontinuation in routine clinical practice
Lee SH, Barnes WG, Schaetzel WP
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