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Department of Health and Human Services
Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)
There is some evidence for this with oral and topical forms in small studies, but the picture for IV glutathione as a skin lightener is much weaker, and results, where reported, tend to be modest and temporary
Cells 8 , 1392 (2019)
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