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"Layer on a daily antioxidant like vitamin C, and never skip your SPF," which she says is "your skins best insurance policy." In addition to retinoids, New York dermatologist Doris Day, MD recommends honing in on innovative ingredients like exosomes for their proven rejuvenation capabilities and ceramides for deep hydration, as well as up-and-coming ingredients like "mTor1 inhibitors," which she says are "a novel class of molecules that are going to revolutionize skin aging." The best in-office and OTC products for GLP-1 users To combat lax skin before it starts, Montclair dermatologist Jeanine Downie, MD recommends a line-up of science-backed serums and treatments