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In phase 3 trials, maximal dose retatrutide demonstrated 29% placebo-adjusted weight loss at 68 weeks (albeit with higher discontinuation rates than semaglutide and tirzepatide)
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This enhanced interaction leads to the phosphorylation of ZEB1 and further stimulation of pancreatic cancer (PC) EMT and metastasis [67]
Benzer ekilde, SURMOUNT-1 almasnda tirzepatid 15 mg grubunda bulant oran %31, ishal oran %23.0 ve kusma oran %12.2 olarak raporlanmtr (3)
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