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Specifically, these two myokines are considered protective proteins released from muscle in response to exercise and are particularly important in responding to oxidative stress and maintaining mitochondrial function [39, 89]

Kabahizi A, Wallace B, Lieu L, Chau D, Dong Y, Hwang ES, Williams KW (2022) Glucagon-like peptide-1 (GLP-1) signalling in the brain: From neural circuits and metabolism to therapeutics

Robbins HA, Clarke CA, Arron ST, Tatalovich Z, Kahn AR, Hernandez BY et al

Calcium, diacylglycerol, cAMP and various phosphate derivatives of myoinositol (phosphatidylinositol and others) are essential secondary messengers involved in the regulation of intracellular signaling cascades, in response to the activation of the TSHR, and are necessary for the production H 2 O 2 and TG synthesis (56)