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For tirzepatide, restart at 2.5 mg weekly
In two participants, there was incidentally found progression of clinically stable or regressed retinopathy (one episode of proliferative retinopathy during placebo use and one nonproliferative sequela during semaglutide use)
In STEP 1, participants without diabetes who received semaglutide 2.4 mg weekly lost an average of 14.9% of their body weight over 68 weeks compared to 2.4% with placebo
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