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Hematologic and biochemical monitoring throughout the trials revealed no concerning patterns in blood counts, liver function tests, kidney function markers, or other laboratory parameters

Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed

Combining this with a PDE-5 medication (Viagra, Cialis) may be a successful combination, but should only be done when your medical provider is aware of your condition and medication use

However, important limitations remain