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The positions of water were primarily refined in Coot based on the receptor focused maps and further inspected with the density in the consensus maps

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However, some meiotic cells were still present in the gld-2 gld-1 prom-1 triple mutant, suggesting that there may be an additional pathway(s) that functions redundantly with the GLD-1, GLD-2 and SCF PROM1 pathways to promote meiotic entry and/or inhibit proliferation (Mohammad et al., 2018)

Toxicology assessments in rats found no organ toxicity at doses up to 10 mg/kg (approximately 1000x the effective dose), no mutagenicity in Ames testing, and no teratogenic effects