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The evidence: Very preliminary
The lid domain and glycine-rich loop are critical for ATP binding, which triggers major shifts in their conformations (Galant et al., In the structures of human and yeast GS, two alanine residues form van der Waals contacts with the glycine moiety of glutathione (Polekhina et al., These structure/function studies established the basis of glutathione versus homoglutathione specificity, but it remains unclear how other glutathione analogs are formed in different plants
Additionally they do not need SUOX SNPs to have this happen (they may have it, but it isnt necessary)
These findings elucidate its potential role in aesthetic and regenerative treatments designed to enhance skin tone and texture
