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Fatigue commonly peaks during dose titration phases and often resolves as tolerance develops and gastrointestinal symptoms diminish

It is not approved for use with certain medications or in individuals with specific health conditions affecting blood pressure or heart health

Surgeons should consider how the timing of elective procedures might shift if GLP-1 therapy is inducing substantial weight loss or anatomical change, which is relevant for bariatric, abdominal or head and neck surgeries