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Brief Introduction and Physiological Function of Glucagon Like Peptide-1 Receptor Agonists Glucagon like peptide-1 (GLP-1) is the second incretin identified in 1983
ANGPTL3 as a drug target in hyperlipidemia and atherosclerosis
Furthermore, exendin-4 has been shown to attenuate lipotoxicity-induced glomerular endothelial cell dysfunction in diabetic ApoE-deficient mice by increasing the ABC transporter A1-mediated cholesterol efflux (Yin et al., 2016)
For something to be added to the WADA Prohibited List, it must meet two of the three inclusion criteria: 1) it has the potential to enhance performance 2) it poses a health risk to athletes and 3) it violates the spirit of sport
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